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According to a study published in the November 24 online problem of Neurology.

This is among the first large scale studies related to epilepsy drugs and breast milk, but we realize more research is needed on the effects of other medicines for epilepsy, some of the newer ones especially, says Meador, a fellow of the American Academy of Neurology . Meador says AAN guidelines recommend that if possible females should avoid taking more than one epilepsy drug at the same time during pregnancy since taking more than one drug has been found to increase the risk of birth defects in comparison to taking only 1 medication. AAN guidelines also recommend that valproate be prevented during pregnancy due to dangers of birth defects and results on cognitive skills..Combinations of lower dosages of BCX4208 with allopurinol showed synergistic results in sUA reduction. These doses of BCX4208 only and in conjunction with allopurinol were generally secure and well-tolerated. In keeping with prior BCX4208 clinical research, reductions in peripheral bloodstream lymphocytes were seen in individuals treated with BCX4208. The process included stopping guidelines for CD4+ cell counts below certain thresholds; simply no subjects were discontinued because of this.

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